Vitamin E

The primary function of vitamin E in the body is as an antioxidant. Vitamin E is a fat-soluble vitamin and is thought to protect cell membranes, which have a high content of fats. Vitamin E may also protect LDL cholesterol against oxidation, helping to protect against coronary artery disease.[102]

Vitamin E may also directly increase glutathione levels. A double-blind trial on diabetic children found that giving 100iu per day of vitamin E for three months increased the blood glutathione levels in the supplemented group by 9%, whereas glutathione levels in the placebo group did not increase. The authors concluded that ‘glutathione level is significantly related to vitamin E level’[103]. Another study on rats fed a high-cholesterol diet found that vitamin E supplementation increased levels of glutathione, and activities of the enzymes glutathione peroxidase and glutathione transferase.[104]



102. Linus Pauling Institute / Jane Higdon, Ph.D.. 2004. Micronutrient Information Center: Vitamin E. [ONLINE] Available at: [Accessed 02 April 15].

103. Jain SK et al. Vitamin E supplementation restores glutathione and malondialdehyde to normal concentrations in erythrocytes of type 1 diabetic children. Diabetes Care. 2000 Sep;23(9):1389-94.

104. Gokkusu, C., et al. Changes of oxidative stress in various tissues by long-term administration of vitamin E in hypercholesterolemic rats. Clin Chim Acta. 328(1-2):155-161, 2003.



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